Athlone is located in the very centre of Ireland on the N6 National primary route between Dublin and Galway.

Its geographical location puts it within easy reach of all population centres. Athlone is fully serviced by public transport. It is on the main rail link from Dublin to Galway/Westport. The North/South axis is served by a combination of national routes.

The navigable River Shannon flows through the centre of the town.